RSO vs FECO: Which Is Safer and More Effective?

Introduction

As medical cannabis use grows across the United States, many patients face a key decision: should they use Rick Simpson Oil (RSO) or Full Extract Cannabis Oil (FECO)? Both are high-potency, full-spectrum cannabis oils, and both offer promising relief for conditions like cancer, chronic pain, and neurological disorders. However, they differ significantly in safety, extraction method, and product consistency (RSO vs FECO).

In this guide, we compare RSO and FECO in terms of safety, efficacy, availability, and user experience so you can make an informed choice in 2025.


What Is RSO?

RSO is a thick, tar-like cannabis oil made using solvents like isopropyl alcohol or naphtha. It contains very high levels of THC (often 70–90%) and includes all the plant’s natural cannabinoids and terpenes.

Originally developed by Rick Simpson to treat his own skin cancer, RSO is commonly used for:

  • Cancer support
  • Severe chronic pain
  • Appetite stimulation
  • Sleep and anxiety relief

While RSO is effective, the use of harsh solvents—especially in home extractions—raises questions about safety and purity.


What Is FECO?

FECO, or Full Extract Cannabis Oil, is also a full-spectrum cannabis oil. However, it’s typically extracted using food-grade ethanol or CO₂, which are safer solvents. It maintains the full cannabinoid profile (including THC, CBD, CBG, and others) and often comes with lab testing to verify its contents.

Patients use FECO for a range of conditions, including:

  • Cancer
  • Inflammatory disorders
  • Epilepsy
  • Autoimmune diseases
  • Chronic pain and sleep disturbances

FECO’s cleaner production methods and lab-tested reliability have made it increasingly popular in licensed dispensaries across the U.S.


Key Differences Between RSO and FECO (RSO vs FECO)

FeatureRSOFECO
Solvent UsedIsopropyl alcohol, naphthaFood-grade ethanol, CO₂
Safety ProfileVariable (risk of residual solvents)High (safer, lab-tested)
Taste & TextureBitter, thick, tar-likeCleaner, more refined
Product ConsistencyOften varies, especially if homemadeStandardized and consistent
AvailabilityCommon in legacy markets and select statesWidely available through dispensaries
Lab TestingOften missing with homemade versionsRequired in licensed sales
Popular UsesCancer, pain, palliative careCancer, epilepsy, inflammation, chronic pain

Which Oil Is Safer to Use?

From a safety perspective, FECO is generally the better choice, particularly because:

  • It’s extracted with clean, food-safe solvents
  • Most dispensaries require third-party lab testing
  • There’s less risk of contamination or solvent residue

RSO can still be safe, especially when sourced from a trusted, lab-tested supplier. However, many RSO products are still made at home or sold without testing, which raises the risk of chemical exposure.

If you are immunocompromised or using cannabis long-term, FECO offers a more medically sound option.


Which Oil Is More Effective?

Effectiveness depends largely on the user, their condition, and the source of the oil:

  • Cancer patients often report strong relief from both RSO and FECO, though FECO offers more consistency
  • Patients with neurological disorders (like epilepsy or MS) prefer FECO because of its purity and microdosing control
  • For severe chronic pain or insomnia, both oils can be effective, but FECO may be more tolerable for new users

In general, RSO has a reputation for being more raw and intense, while FECO is viewed as safer, smoother, and easier to dose.


Availability in the U.S. (2025)

Both RSO and FECO are available in many U.S. states with legal medical cannabis programs.

  • FECO is more common in dispensaries and typically comes in capsules, syringes, or tinctures
  • RSO is also widely available but may be labeled as “Phoenix Tears”
  • Some dispensaries offer both, allowing patients to choose based on comfort level and doctor recommendation

Always ensure any product you purchase includes lab results (COAs) and comes from a licensed dispensary or verified supplier (RSO vs FECO).


How to Choose Between RSO and FECO

Here are a few questions to help you decide:

  • Are you sensitive to solvents or require ultra-clean products? → Choose FECO
  • Are you following Rick Simpson’s 60g/90-day cancer protocol? → Use RSO
  • Do you need standardized dosing with lab verification? → Go with FECO
  • Are you on a tight budget and willing to source carefully? → RSO may be more accessible

Whichever you choose, always start with a low dose, monitor your response, and consult with a medical cannabis provider.


Final Thoughts: RSO or FECO? The Right Oil Depends on You

Both RSO and FECO offer potent, full-spectrum cannabis therapy, but they cater to different needs and preferences. RSO is powerful and trusted by many long-time users, but it carries more safety concerns unless properly sourced. FECO is cleaner, better regulated, and increasingly recommended by cannabis doctors for patients needing high THC relief with low risk.

No matter which oil you choose, prioritize safety, lab testing, and professional guidance. Your health deserves nothing less.


Looking to compare trusted RSO and FECO products available nationwide? Explore our therapeutic oil lineup


Learn more about cannabis oil types from ProjectCBD.org

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