Rick Simpson Oil Side Effects & Safety Tips

Rick Simpson Oil (RSO) Side Effects & Safety Tips

Rick Simpson Oil (RSO) is one of the most powerful cannabis extracts available — and while many people praise its therapeutic benefits, especially for conditions like cancer and chronic pain, it’s important to understand the potential side effects it may cause.

Because of its high THC concentration, RSO can produce strong psychoactive effects and physical sensations, especially for those who are new to cannabis or unfamiliar with high-potency products. In this post, we’ll break down the common side effects of RSO and share important safety tips for first-time and long-term users.


Common Side Effects of RSO

Though RSO is used by many for its healing potential, some users may experience temporary side effects, especially during the early stages of use. These effects are typically related to its THC content, which can impact both your mind and body.

Here are the most commonly reported side effects of RSO:

  • Drowsiness – A strong sense of sedation or sleepiness is common, especially at higher doses.
  • Dry Mouth – Also known as “cottonmouth,” this is a frequent side effect of THC.
  • Red Eyes – Bloodshot or irritated eyes may occur shortly after consumption.
  • Increased Appetite – Commonly referred to as “the munchies,” THC can cause hunger.
  • Slowed Reaction Time – THC affects motor function and reflexes, so avoid driving.
  • Anxiety or Paranoia – High doses may induce nervousness in some users, especially beginners.
  • Dizziness or Lightheadedness – This can happen during the adjustment phase or from standing up too quickly.

These effects are usually short-term and tend to fade as your body adjusts to the oil. However, starting with the right dosage is key to avoiding discomfort.


How to Use RSO Safely

Because of its potency, it’s important to approach RSO with caution — especially if you’re new to THC-heavy products.

Here are safety recommendations to help you get the most out of RSO while minimizing side effects:

Start Small

Follow the original Rick Simpson protocol, which recommends beginning with a dose half the size of a grain of rice, or about 30mg of oil.

Increase Gradually

Give your body time to adjust. Slowly increase your dose over days or weeks as your tolerance builds. Avoid large increases too quickly.

Stay Hydrated

To reduce dry mouth and dizziness, drink water regularly throughout the day.

Don’t Drive or Operate Machinery

Until you know how RSO affects you, it’s best to avoid driving or using heavy equipment.

Store RSO Properly

Keep your oil stored in a cool, dark place and out of reach of children and pets.

Talk to a Healthcare Provider

If you have underlying conditions or take prescription medications, consult with a healthcare provider before starting RSO.


Final Thoughts: Managing RSO Side Effects

RSO is a powerful tool in the world of medical cannabis, offering support for pain, cancer, inflammation, and neurological issues. But like any potent medicine, it comes with potential side effects — most of which can be managed with proper dosing and care.

By starting low, going slow, and listening to your body, most users are able to safely enjoy the benefits of Rick Simpson Oil without major discomfort.


Looking to get started with RSO?
Explore our full range of lab-tested Rick Simpson Oil products with dosage guides and full-spectrum formulas — crafted for effectiveness and purity.

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